Preliminary evidence of the effects of a novel antioxidant supplement in reducing oxidative stress in patients with senile cataract

Author:

Himori Noriko,Kunikata Hiroshi,Nakazawa Toru

Publisher

Springer Science and Business Media LLC

Subject

Ophthalmology

Reference6 articles.

1. Chylack LT Jr, Brown NP, Bron A, Hurst M, Kopcke W, Thien U, Schalch W (2002) The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Ophthalmic Epidemiol 9:49–80. https://doi.org/10.1076/opep.9.1.49.1717

2. Maraini G, Williams SL, Sperduto RD, Ferris F, Milton RC, Clemons TE, Rosmini F, Ferrigno L (2008) A randomized, double-masked, placebo-controlled clinical trial of multivitamin supplementation for age-related lens opacities. Clinical trial of nutritional supplements and age-related cataract report no. 3. Ophthalmology 115:599–607. https://doi.org/10.1016/j.ophtha.2008.01.005

3. Maekawa S, Sato K, Fujita K, Daigaku R, Tawarayama H, Murayama N, Moritoh S, Yabana T, Shiga Y, Omodaka K, Maruyama K, Nishiguchi KM, Nakazawa T (2017) The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation. Sci Rep 7:6885. https://doi.org/10.1038/s41598-017-06969-4

4. Maekawa S, Sato K, Kokubun T, Himori N, Yabana T, Ohno-Oishi M, Shi G, Omodaka K, Nakazawa T (2022) A plant-derived antioxidant supplement prevents the loss of retinal ganglion cells in the retinas of NMDA-injured mice. Clin Ophthalmol (Auckland, NZ) 16:823–832. https://doi.org/10.2147/opth.s354958

5. Hayashi R, Hayashi S, Arai K, Sakai M, Okamoto H, Chikuda M (2014) The gender-differentiated antioxidant effects of a lutein-containing supplement in the aqueous humor of patients with senile cataracts. Exp Eye Res 129:5–12. https://doi.org/10.1016/j.exer.2014.10.009

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