PTHrP, PTHr, and FGFR3 are involved in the process of endochondral ossification in human osteophytes

Author:

Huch Klaus,Kleffner Sandra,Stöve Johannes,Puhl Wolfhart,Günther Klaus-Peter,Brenner Rolf Erwin

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Medical Laboratory Technology,Molecular Biology,Histology

Reference38 articles.

1. Aigner T, Dietz U, Stoss H, Mark K von der (1995) Differential expression of collagen types I, II, III, and X in human osteophytes. Lab Invest 73:236–243

2. Amizuka N, Henderson JE, White JH, Karaplis AC, Goltzman D, Sasaki T, Ozawa H (2000a) Recent studies on the biological action of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in cartilage and bone. Histol Histopathol 15:957–970

3. Amizuka N, Ozawa H, Sasaki T (2000b) The biological action of parathyroid hormone-related peptide (PTHrP) and fibroblast growth factor receptor 3 (FGFR3) on bone and cartilage. Kaibogaku Zasshi 75:415–425

4. Bovée JV, Broek LJ van den, Cleton-Jansen AM, Hogendoorn PC (2000) Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma. Lab Invest 80:1925–1934

5. Chen L, Li C, Qiao W, Xu X, Deng C (2001) A Ser(365)→Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia. Hum Mol Genet 10:457–465

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