Altered thyroid status affects myocardial expression of connexin-43 and susceptibility of rat heart to malignant arrhythmias that can be partially normalized by red palm oil intake

Author:

Bačová Barbara Szeiffová,Vinczenzová Csilla,Žurmanová Jitka,Kašparová Dita,Knezl Vladimír,Beňová Tamara Egan,Pavelka Stanislav,Soukup Tomáš,Tribulová Narcisa

Funder

Slovak Grant Agency, VEGA

Grantová Agentura eské Republiky

APVV

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Medical Laboratory Technology,Molecular Biology,Histology,General Agricultural and Biological Sciences,General Medicine,Anatomy

Reference43 articles.

1. Almeida NA, Cordeiro A, Machado DS, Souza LL, Ortiga-Carvalho TM, Campos-de-Carvalho AC, Wondisford FE, Pazos-Moura CC (2009) Connexin40 messenger ribonucleic acid is positively regulated by thyroid hormone (TH) acting in cardiac atria via the TH receptor. Endocrinology 150:546–554

2. Benova T, Viczenczova C, Radosinska J, Bacova B, Knezl V, Dosenko V, Weismann P, Zeman M, Navarova J, Tribulova N (2013) Melatonin attenuates hypertension-related proarrhythmic myocardial maladaptation of connexin-43 and propensity of the heart to lethal arrhythmias. Can J Physiol Pharmacol 91:633–639

3. Benova T, Knezl V, Viczenczova C, Bacova BS, Radosinska J, Tribulova N (2015) Acute anti-fibrillating and defibrillating potential of atorvastatin, melatonin, eicosapentaenoic acid and docosahexaenoic acid demonstrated in isolated heart model. J Physiol Pharmacol 66:83–89

4. Biondi B, Palmieri EA, Fazio S, Cosco C, Nocera M, Sacca L, Filetti S, Lombardi G, Perticone F (2000) Endogenous subclinical hyperthyroidism affects quality of life and cardiac morphology and function in young and middle-aged patients. J Clin Endocrinol Metab 85:4701–4705

5. Cooklin M, Wallis WR, Sheridan DJ, Fry CH (1998) Conduction velocity and gap junction resistance in hypertrophied, hypoxic guinea-pig left ventricular myocardium. Exp Physiol 83:763–770

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