Extreme resistance to the novel siderophore-cephalosporin cefiderocol in an extensively drug-resistant Klebsiella pneumoniae strain causing fatal pneumonia with sepsis: genomic analysis and synergistic combinations for resistance reversal
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Microbiology (medical),General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s10096-023-04671-0.pdf
Reference23 articles.
1. Sato T, Yamawaki K (2019) Cefiderocol: discovery, chemistry, and in vivo profiles of a novel siderophore cephalosporin. Clin Infect Dis 13(69):S538–S543. https://doi.org/10.1093/cid/ciz826
2. Naseer S, Weinstein EA, Rubin DB, Suvarna K, Wei X, Higgins K et al (2021) US Food and Drug Administration (FDA): benefit-risk considerations for cefiderocol (Fetroja®). Clin Infect Dis 15(72):e1103–e1111. https://doi.org/10.1093/cid/ciaa1799
3. Ito A, Sato T, Ota M, Takemura M, Nishikawa T, Toba S et al (2017) In vitro antibacterial properties of cefiderocol, a novel siderophore cephalosporin, against gram-negative bacteria. Antimicrob Agents Chemother 21(62):e01454-e1517. https://doi.org/10.1128/AAC.01454-17
4. Streling AP, Al Obaidi MM, Lainhart WD, Zangeneh T, Khan A, Dinh AQ et al (2021) Evolution of cefiderocol non-susceptibility in Pseudomonas aeruginosa in a patient without previous exposure to the antibiotic. Clin Infect Dis 6(73):e4472–e4474. https://doi.org/10.1093/cid/ciaa1909
5. Coppi M, Antonelli A, Niccolai C, Bartolini A, Bartolini L, Grazzini M et al (2022) Nosocomial outbreak by NDM-1-producing Klebsiella pneumoniae highly resistant to cefiderocol, Florence, Italy, August 2021 to June 2022. Euro Surveill 27(27):2200795. https://doi.org/10.2807/1560-7917.ES.2022.27.43.2200795
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1. High efficacy and enhanced synergistic activity of the novel siderophore-cephalosporin cefiderocol against multidrug-resistant and extensively drug-resistant Klebsiella pneumoniae from inpatients attending a single hospital in the United Arab Emirates;Journal of Infection and Public Health;2023-12
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