Recent advances in targeting DNA repair pathways for the treatment of ovarian cancer and their clinical relevance
Author:
Funder
Japan Agency for Medical Research and Development
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology,General Medicine,Surgery
Link
http://link.springer.com/article/10.1007/s10147-017-1137-7/fulltext.html
Reference69 articles.
1. Tomkinson AE, Chen L, Dong Z et al (2001) Completion of base excision repair by mammalian DNA ligases. Prog Nucleic Acid Res Mol Biol 68:151–164
2. Jasin M (2002) Homologous repair of DNA damage and tumorigenesis: the BRCA connection. Oncogene 21:8981–8993
3. Ashworth A (2008) A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol 26:3785–3790
4. Martin SA, Lord CJ, Ashworth A (2008) DNA repair deficiency as a therapeutic target in cancer. Curr Opin Genet Dev 18:80–86
5. Yap TA, Sandhu SK, Carden CP et al (2011) Poly(ADP-ribose) polymerase (PARP) inhibitors: exploiting a synthetic lethal strategy in the clinic. CA Cancer J Clin 61:31–49
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