Synthesis and antimicrobial activity of molecular hybrids based on eugenol and chloramphenicol pharmacophores

Author:

Oliveira Lucas M.ORCID,Siqueira Fallon S.ORCID,Silva Michelle T.ORCID,Machado José V. C.ORCID,Cordeiro Cleydson F.ORCID,Diniz Lívia F.ORCID,Campos Marli M. A.ORCID,Franco Lucas L.ORCID,Souza Thiago B.ORCID,Hawkes Jamie A.ORCID,Carvalho Diogo T.ORCID

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Microbiology

Reference42 articles.

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2. Azevedo-Barbosa H, Vale BPd, Rossi GG, Siqueira FdS, Guterres KB, Campos MMAd, Santos Td, Hawkes JA, Dias DF, Lavorato SN, Souza TBd, Carvalho DT (2021) Design, synthesis, antimicrobial evaluation and in silico studies of eugenol - sulfonamide hybrids. Chem Biodivers 18:e2100066. https://doi.org/10.1002/cbdv.202100066

3. Berkov-Zrihen Y, Green KD, Labby LJ, Freldman M, Garneau-Tsodikova S, Fridman M (2013) Synthesis and evaluation of hetero- and homodimers of ribosome targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. J Med Chem 56:5613–5625. https://doi.org/10.1021/jm400707f

4. Brady AJ, Gray JD (1957) The treatment of fungous infection of the skin with nicetin. Can Med Assoc J 76:725–729 (PMID: 13426911)

5. Brancaglion GA, Toyota AE, Cardoso Machado JV, Fernandes AA, Silveira AT, Boas DFV, dos Santos EG, Caldas IS, Carvalho DT (2018) In vitro and in vivo trypanocidal activities of 8-methoxy-3-(4-nitrobenzoyl)-6-propyl-2H-cromen-2-one, a new synthetic coumarin of low cytotoxicity against mammalian cells. Chem Biol Drug Des 92:1888–1898. https://doi.org/10.1111/cbdd.13362

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