S-adenosyl-L-methionine reverses the cholestatic effect of ethinylestradiol in rat hepatocytes by increasing its catabolism

Author:

Larrauri Amparo,Castell Jos� V.,Garrido Guillermo,Berenguer Joaqu�n,G�mez-lech�n M. Jos�

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Cell Biology,Toxicology

Reference34 articles.

1. FADACHI, Y., NANNO, T., and KANBE., A. (1986). ?The effects of S-adenosyl methionine on intrahepatic cholestasis.? Jpn. Arch. Int. Med. 6:185?192.

2. ARIAS, A.M., ADACHI, Y., and TRAN, T. (1983). ?Ethinyl estradiol cholestasis: a disease of the sinusoidal domain of hepatocyte plasma membrane.? Hepatology 3:872.

3. BERR, F., SIMON, F.R., and REICHEN, J. (1987). ?Ethinylestradiol impairs bile salt uptake and Na-K pump function of rat hepatocytes.? Am. J. Physiol. 247:G437.

4. BOELSTERLI, U.A., RAKHIT, G., and BALAZS, T. (1983). ?Modulation by S-adenosyl-Lmethionine of hepatic Na+/K?-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis.? Hepatology 3:12?17.

5. BOYER, J.L. (1980). ?New concepts of mechanisms of hepatocyte bile formation.? Physiol. Rev. 60:302?326.

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