Lead and Cadmium Co-exposure Mediated Toxic Insults on Hepatic Steroid Metabolism and Antioxidant System of Adult Male Rats

Author:

Pandya Chirayu D.,Pillai Prakash P.,Gupta Sarita S.

Publisher

Springer Science and Business Media LLC

Subject

Biochemistry (medical),Inorganic Chemistry,Clinical Biochemistry,General Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference44 articles.

1. Vallee BL, Ulmer DD (1972) Biochemical effects of mercury, cadmium and lead. Annu Rev Biochem 41(10):91–128

2. Patra RC, Swarup D, Senapati SK (1999) Effects of cadmium on lipid peroxides and superoxide dismutase in hepatic, renal and testicular tissue of rats. Vet Hum Toxicol 41(2):65–67

3. Wilson VS, LeBlanc GA (1998) Endosulfan elevates testosterone biotransformation and clearance in CD-1 mice. Toxicol Appl Pharmacol 148:158–168

4. deBethizy JD, Hayes JR (1994) Metabolism: a determinant of toxicity. In: Hayes AW (ed) Principles and methods of toxicology, 3rd edn. Raven, New York, pp 59–100

5. Waxman DJ, Ko A, Walsh C (1983) Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbitolinduced rat liver. J Biol Chem 258:11937–11947

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