Abstract
AbstractAnthrax is endemic in Georgia, as are multiple zoonotic poxviruses. Poxvirus-associated infections share some clinical manifestations and exposure risks with anthrax, and so it is important to distinguish between the two. With this in mind, an archived collection of anthrax-negative DNA samples was retrospectively screened for poxviruses, and of the 148 human samples tested, 64 were positive. Sequence analysis confirmed the presence of orf virus, bovine papular stomatitis virus, and pseudocowpox virus. This study provides evidence of previously unrecognized poxvirus infections in Georgia and highlights the benefit of the timely identification of such infections by improving laboratory capacity.
Publisher
Springer Science and Business Media LLC
Subject
Virology,General Medicine
Reference14 articles.
1. Zeegelaar JE, Faber WR (2008) Imported tropical infectious ulcers in travelers. Am J Clin Dermatol 9:219–232
2. Tsanava SA, Marennikova SS, Sakvarelidze LA, Shelukhina EM, Ianova NN (1989) Isolation of cowpox virus from the red-tailed jird. Vopr Virusol 34:95
3. Tsanava SA, Sakvarelidze LA, Shelukhina EM (1989) Serologic survey of wild rodents in Georgia for antibodies to orthopoxviruses. Acta Virol 33:91
4. Vora NM, Li Y, Geleishvili M, Emerson GL, Khmaladze E, Maghlakelidze G, Navdarashvili A, Zakhashvili K, Kokhreidze M, Endeladze M, Mokverashvili G, Satheskumar PS, Gallardo-Romero N, Goldsmith CS, Metcalfe MG, Damon I, Maes EF, Reynolds MG, Morgan J, Carroll DS (2015) Human infection with a zoonotic orthopoxvirus in the country of Georgia. N Engl J Med 372:1223–1230
5. Chakhunashvili G, Carlson BF, Power L, Khmaladze E, Tsaguria D, Gavashelidze M, Zakhashvili K, Imnadze P, Boulton ML (2018) Parapoxvirus infections in the country of Georgia: a case series. Am J Trop Med Hyg 98:1870–1875
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献