Development of a porcine reproductive and respiratory syndrome virus-like-particle-based vaccine and evaluation of its immunogenicity in pigs

Author:

Binjawadagi Basavaraj,Lakshmanappa Yashavanth Shaan,Longchao Zhu,Dhakal Santosh,Hiremath Jagadish,Ouyang Kang,Shyu Duan-Liang,Arcos Jesus,Pengcheng Shang,Gilbertie Aaron,Zuckermann Federico,Torrelles Jordi B.,Jackwood Daral,Fang Ying,Renukaradhya Gourapura J.

Funder

National Pork Board

Publisher

Springer Science and Business Media LLC

Subject

Virology,General Medicine

Reference51 articles.

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2. Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Torrelles JB, Renukaradhya GJ (2014) An innovative approach to induce cross-protective immunity against porcine reproductive and respiratory syndrome virus in the lungs of pigs through adjuvanted nanotechnology-based vaccination. Int J Nanomedicine 9:1519–1535

3. Binjawadagi B, Dwivedi V, Manickam C, Ouyang K, Wu Y, Lee LJ, Torrelles JB, Renukaradhya GJ (2014) Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs. Int J Nanomedicine 9:679–694

4. Botner A, Strandbygaard B, Sorensen KJ, Have P, Madsen KG, Madsen ES, Alexandersen S (1997) Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine. Vet Rec 141:497–499

5. Burgara-Estrella A, Diaz I, Rodriguez-Gomez IM, Essler SE, Hernandez J, Mateu E (2013) Predicted peptides from non-structural proteins of porcine reproductive and respiratory syndrome virus are able to induce IFN-gamma and IL-10. Viruses 5:663–677

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