A positively charged surface patch on the pestivirus NS3 protease module plays an important role in modulating NS3 helicase activity and virus production
Author:
Funder
National Key Research and Development Program of China
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Virology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00705-021-05055-5.pdf
Reference50 articles.
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2. Becher P, Orlich M, Thiel HJ (1998) Complete genomic sequence of border disease virus, a pestivirus from sheep. J Virol 72:5165–5173
3. Beran RK, Serebrov V, Pyle AM (2007) The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate. J Bio Chem 282:34913–34920
4. Beran RK, Pyle AM (2008) Hepatitis C viral NS3-4A protease activity is enhanced by the NS3 helicase. J Bio Chem 283:29929–29937
5. Bintintan I, Meyers G (2010) A new type of signal peptidase cleavage site identified in an RNA virus polyprotein. J Bio Chem 285:8572–8584
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