Conflicting Effects of Wnt-5a in Ulcerative Colitis: You Wnt Some, You Lose Some
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Physiology
Link
https://link.springer.com/content/pdf/10.1007/s10620-022-07542-4.pdf
Reference8 articles.
1. Kobayashi T, Siegmund B, Le Berre C et al. Ulcerative colitis. Nat Rev Dis Primers. 2020;6:74. https://doi.org/10.1038/s41572-020-0205-x.
2. Uchiyama K, Takagi T, Mizushima K, et al. Investigation on the inhibitory effect of Wnt-5a on colonic mucosal inflammation in patients with ulcerative colitis. Dig Dis Sci. (Epub ahead of print). https://doi.org/10.1007/s10620-022-07537-1.
3. Hughes KR, Sablitzky F, Mahida YR. Expression profiling of Wnt family of genes in normal and inflammatory bowel disease primary human intestinal myofibroblasts and normal human colonic crypt epithelial cells. Inflamm Bowel Dis. 2011;17:213–220. https://doi.org/10.1002/ibd.21353.
4. Kikuchi A, Yamamoto H, Sato A, Matsumoto S. Wnt5a: its signalling, functions and implication in diseases. Acta Physiol (Oxf). 2012;204:17–33. https://doi.org/10.1111/j.1748-1716.2011.02294.x.
5. Uchiyama K, Sakiyama T, Hasebe T et al. Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development. Sci Rep. 2016;6:32094. https://doi.org/10.1038/srep32094.
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