GI-Safer Aspirin: Sometimes Sugar Coating Helps
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Physiology
Link
http://link.springer.com/content/pdf/10.1007/s10620-016-4236-9.pdf
Reference10 articles.
1. Kawasaki K, Kurahara K, Yanai S, Kochi S, Fuchigami T, Matsumoto T. Low-dose aspirin and non-steroidal anti-inflammatory drugs increase the risk of bleeding in patients with gastroduodenal ulcer. Dig Dis Sci. 2015;60:1010–1015.
2. Kangwan N, Park JM, Hahm KB. Development of GI-safe NSAID; progression from the bark of willow tree to modern pharmacology. Curr Opin Pharmacol. 2014;19:17–23.
3. Wallace JL, Syer S, Denou E, et al. Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. Gastroenterology. 2011;141:1314–1322.
4. Singh DP, Borse SP, Nivsarkar M. A novel model for NSAID induced gastroenteropathy in rats. J Pharmacol Toxicol Methods. 2016;78:66–75.
5. Lin LS, Kayasuga-Kariya Y, Nakamura S, et al. Co-lyophilized aspirin with tehalose causes less injury to human gastric cells and gastric mucosa of rats. Dig Dis Sci (Epub ahead of print). doi: 10.1007/s10620-016-4209-z .
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