Thalidomide Attenuates Colitis and Is Associated with the Suppression of M1 Macrophage Polarization by Targeting the Transcription Factor IRF5
Author:
Funder
the National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Physiology
Link
https://link.springer.com/content/pdf/10.1007/s10620-021-07067-2.pdf
Reference40 articles.
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2. Krishnan K, Arnone B, Buchman A. Intestinal growth factors: potential use in the treatment of inflammatory bowel disease and their role in mucosal healing. Inflamm Bowel Dis 2011;17:410–422.
3. Sandborn WJ, Peyrin-Biroulet L, Zhang J et al. Efficacy and safety of Etrasimod in a phase 2 randomized trial of patients with ulcerative colitis. Gastroenterology 2020;158:550–561.
4. Franks ME, Macpherson GR, Figg WD. Thalidomide. The Lancet 2004;363:1802–1811.
5. Vasiliauskas EA, Kam LY, Abreu-Martin MT et al. An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn’s disease. Gastroenterology 1999;117:1278–1287.
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