A Higher Dose Requirement of Tacrolimus in Active Crohn's Disease May Be Related to a High Intestinal P-Glycoprotein Content
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Physiology
Link
http://link.springer.com/content/pdf/10.1007/s10620-005-3053-3.pdf
Reference28 articles.
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3. Christians U, Jacobsen W, Benet LZ, Lampen A: Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet 41:813–851, 2002
4. Fellermann K, Ludwig D, Stahl M, et al.: Steroid–unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK 506). Am J Gastroenterol 93:1860–1866, 1998
5. Lowry PW, Weaver AL, Tremaine WJ, Sandborn WJ: Combination therapy with oral tacrolimus (FK 506) and azathioprine or 6-mercaptopurine for treatment-refractory Crohn's disease perianal fistula. Inflamm Bowel Dis 5:239–245, 1999
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