Urokinase plasminogen activator as an anti-metastasis target: inhibitor design principles, recent amiloride derivatives, and issues with human/mouse species selectivity-Reference-Cited by-同舟云学术

Urokinase plasminogen activator as an anti-metastasis target: inhibitor design principles, recent amiloride derivatives, and issues with human/mouse species selectivity

Published:2022-01-06 Issue:1 Volume:14 Page:277-301
ISSN:1867-2450
Container-title:Biophysical Reviews
language:en
Short-container-title:Biophys Rev

Author:

El Salamouni Nehad S,Buckley Benjamin J.,Ranson Marie,Kelso Michael J.,Yu Haibo^ORCID

Funder

National Health and Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology,Biophysics

Link

https://link.springer.com/content/pdf/10.1007/s12551-021-00921-7.pdf

Reference142 articles.

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2. Alipranti FX, Masih M, Torres-Paris C, Komives EA (2020) S195A is a catalytically inactive mutant of the protease domain of the urokinase-type plasminogen activator (uPA). Biophys J 118((1 Supplement 1)):50a. https://doi.org/10.1016/j.bpj.2019.11.455

3. Alpízar-Alpízar W, Christensen IJ, Santoni-Rugiu E, Skarstein A, Ovrebo K, Illemann M, Laerum OD (2012) Urokinase plasminogen activator receptor on invasive cancer cells: a prognostic factor in distal gastric adenocarcinoma. Int J Cancer 131(4):E329–E336. https://doi.org/10.1002/ijc.26417

4. Andersen LM, Wind T, Hansen HD, Andreasen PA (2008) A cyclic peptidylic inhibitor of murine urokinase-type plasminogen activator: changing species specificity by substitution of a single residue. Biochem J 412(3):447–457. https://doi.org/10.1042/BJ20071646

5. Andreasen PA, Egelund R, Petersen HH (2000) The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57(1):25–40. https://doi.org/10.1007/s000180050497

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