Double the trouble: giant proteins with dual kinase activity in the heart
Author:
Funder
National Institutes of Health
American Heart Association
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology,Biophysics
Link
https://link.springer.com/content/pdf/10.1007/s12551-020-00715-3.pdf
Reference44 articles.
1. Ackermann MA, Shriver M, Perry NA, Hu LY, Kontrogianni-Konstantopoulos A (2014) Obscurins: Goliaths and Davids take over non-muscle tissues. PLoS One 9(2):e88162. https://doi.org/10.1371/journal.pone.0088162
2. Agrawal PB, Pierson CR, Joshi M, Liu X, Ravenscroft G, Moghadaszadeh B, Talabere T, Viola M, Swanson LC, Haliloglu G, Talim B, Yau KS, Allcock RJ, Laing NG, Perrella MA, Beggs AH (2014) SPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy. Am J Hum Genet 95(2):218–226. https://doi.org/10.1016/j.ajhg.2014.07.004
3. Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S (2001) The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res 89(11):1065–1072. https://doi.org/10.1161/hh2301.100981
4. Benian GM, Tinley TL, Tang X, Borodovsky M (1996) The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains. J Cell Biol 132(5):835–848. https://doi.org/10.1083/jcb.132.5.835
5. Borisov AB, Raeker MO, Kontrogianni-Konstantopoulos A, Yang K, Kurnit DM, Bloch RJ, Russell MW (2003) Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth. Biochem Biophys Res Commun 310(3):910–918. https://doi.org/10.1016/j.bbrc.2003.09.035
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Alterations in cytoskeletal and Ca2+ cycling regulators in atria lacking the obscurin Ig58/59 module;Frontiers in Cardiovascular Medicine;2023-04-13
2. PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties;Open Biology;2023-04
3. Combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy;2022-08-24
4. The role of junctophilin proteins in cellular function;Physiological Reviews;2022-07-01
5. Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis;Brain;2021-12-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3