Quality of Life Improves with Alemtuzumab Over 6 Years in Relapsing-Remitting Multiple Sclerosis Patients with or without Autoimmune Thyroid Adverse Events: Post Hoc Analysis of the CARE-MS Studies

Author:

Bertolotto Antonio,Arroyo Rafael,Celius Elisabeth G.,Comi Giancarlo,Havrdova Eva Kubala,Honeycutt William David,Hunter Samuel F.,Izquierdo Guillermo,Kornek Barbara,Miller Tamara,Mitsikostas Dimos D.,Singer Barry A.,Ziemssen Tjalf,Chung Luke,Daizadeh Nadia,Afsar Salman,Hashemi Lobat,Senior Peter

Funder

Sanofi

Bayer HealthCare Pharmaceuticals

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical),Neurology

Reference27 articles.

1. Berger JR. Functional improvement and symptom management in multiple sclerosis: clinical efficacy of current therapies. Am J Manag Care. 2011;17(Suppl 5):S146–53.

2. Sorensen PS. Balancing the benefits and risks of disease-modifying therapy in patients with multiple sclerosis. J Neurol Sci. 2011;311(Suppl 1):S29–34.

3. Cohen JA, Coles AJ, Arnold DL, et al. Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial. Lancet. 2012;380(9856):1819–28.

4. Coles AJ, Twyman CL, Arnold DL, et al. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet. 2012;380(9856):1829–39.

5. Fox EJ, Brassat D, Alroughani R, et al. Alemtuzumab provides durable efficacy over 6 years in patients with active relapsing-remitting multiple scle.rosis and an inadequate response to prior therapy in the absence of continuous treatment (CARE-MS II). Neurology. 2017;88(Suppl 16):S24.006.

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