Variability in drug metabolism: importance of genetic constitution
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science,Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/BF01960741.pdf
Reference37 articles.
1. Breimer DD, Danhof M. Interindividual differences in pharmacokinetics and drug metabolism. In: Breimer DD, ed. Towards better safety of drugs and pharmaceutical products. Amsterdam: Elsevier/North Holland Biomedical Press, 1980:117–41.
2. Sjöqvist F, Von Bahr Ch: Interindividual differences in drug oxidation: clinical importance. Drug Metab Dispos 1973;1:469–82.
3. Holford NHG, Sheiner LB. Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models. Clin Pharmacokinet 1981;6:429–53.
4. Meyer UA, Gut J, Kronbach T, et al. The molecular mechanism of two common polymorphisms of drug oxidation — evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation. Xenobiotica 1986;16:449–65.
5. Eichelbaum M. Defective oxidation of drugs: pharmacokinetic and therapeutic implications. Clin Pharmacokinet 1982;7:1–22.
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4. Metabolism of the contraceptive steroid desogestrel by human liver in vitro;Journal of Steroid Biochemistry;1990-02
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