First pass pharmacokinetics of methohexital in experimental liver disease of the rat

Author:

Epping J.,Heusler H.,Brachtel D.,Richter E.

Publisher

Vieweg+Teubner Verlag

Reference12 articles.

1. Breimer, D. D.: Pharmacokinetics of methohexitone following intravenous infusion in humans. Brit. J., Anaesth. 48, 643 (1976)

2. Bush, M. T., Berry, G., Hume, A.: Ultra-short-acting barbiturates as oral hypnotic agents in man. Clin. Pharmac. Therap. 7, 373 (1966)

3. Heusler, H., Epping, J., Heusler, S., Richter, E., Vermeulen, N. P. E., Breimer, D. D.: Simultaneous determination of blood concentrations of methohexital and its hydroxymetabolite by gaschromatography and identification of 4-hydroxymethohexital by GC-MS (in press)

4. Lehmann, Ch.: Das Ultrakurznarkotikum Methohexital. Anaesthesiology and Resuscitation 57. Springer-Verlag-Berlin—Heidelberg—New York (1972)

5. Levin, W., Sernatinger, E., Jacobsen, M., Kuntzman, R.: Destruction of cytochrome p 450 by secobarbital and other barbiturates containing ally! groups. Science 16, 1341 (1972)

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