Multi-functionality of proteins involved in GPCR and G protein signaling: making sense of structure–function continuum with intrinsic disorder-based proteoforms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00018-019-03276-1.pdf
Reference226 articles.
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3. Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP, Buneman OP, Davenport AP, McGrath JC, Peters JA, Spedding M, Catterall WA, Fabbro D, Davies JA, Nc I (2016) The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Res 44(D1):D1054–D1068. https://doi.org/10.1093/nar/gkv1037
4. Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63(6):1256–1272. https://doi.org/10.1124/mol.63.6.1256
5. Flock T, Hauser AS, Lund N, Gloriam DE, Balaji S, Babu MM (2017) Selectivity determinants of GPCR–G-protein binding. Nature 545(7654):317–322. https://doi.org/10.1038/nature22070
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