PAI-1 production by reactive astrocytes drives tissue dysfibrinolysis in multiple sclerosis models-Reference-Cited by-同舟云学术

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PAI-1 production by reactive astrocytes drives tissue dysfibrinolysis in multiple sclerosis models

Published:2022-05-28 Issue:6 Volume:79 Page:
ISSN:1420-682X
Container-title:Cellular and Molecular Life Sciences
language:en
Short-container-title:Cell. Mol. Life Sci.

Author:

Lebas Héloïse,Guérit Sylvaine,Picot Audrey,Boulay Anne Cécile,Fournier Antoine,Vivien Denis,Cohen Salmon Martine,Docagne Fabian,Bardou Isabelle^ORCID

Funder

Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation

INSERM

Conseil régional de Normandie

Fondation Recherche Médicale

Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00018-022-04340-z.pdf

Reference43 articles.

1. Petersen MA, Ryu JK, Akassoglou K (2018) Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics. Nat Rev Neurosci 19(5):283–301

2. Gveric D, Hanemaaijer R, Newcombe J, van Lent NA, Sier CF, Cuzner ML (2001) Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage. Brain 124(Pt 10):1978–1988

3. Gveric D, Herrera B, Petzold A, Lawrence DA, Cuzner ML (2003) Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors. Brain 126(Pt 7):1590–1598

4. Ryu JK, Petersen MA, Murray SG, Baeten KM, Meyer-Franke A, Chan JP et al (2015) Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation. Nat Commun 6:8164

5. Docagne F, Nicole O, Marti HH, MacKenzie ET, Buisson A, Vivien D (1999) Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia. FASEB J 13(11):1315–1324

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