MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer’s disease-Reference-Cited by-同舟云学术

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MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer’s disease

Published:2015-07-23 Issue:1 Volume:73 Page:217-236
ISSN:1420-682X
Container-title:Cellular and Molecular Life Sciences
language:en
Short-container-title:Cell. Mol. Life Sci.

Author:

Baranger Kévin,Marchalant Yannick,Bonnet Amandine E.,Crouzin Nadine,Carrete Alex,Paumier Jean-Michel,Py Nathalie A.,Bernard Anne,Bauer Charlotte,Charrat Eliane,Moschke Katrin,Seiki Mothoharu,Vignes Michel,Lichtenthaler Stefan F.,Checler Frédéric,Khrestchatisky Michel,Rivera Santiago

Funder

Agence Nationale de la Recherche

LECMA Vaincre l'Alzheimer

Association France Alzheimer

Fonds Européen de Développement Régional FEDER in PACA

Bavarian-French University Center

Deutsche Forschungsgemeinschaft

Fondation pour la Recherche Médicale

LABEX DISTALZ

Marie Curie International Reintegration Grant

Fondation Plan Alzheimer

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/article/10.1007/s00018-015-1992-1/fulltext.html

Reference69 articles.

1. De Strooper B (2010) Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev 90(2):465–494. doi: 10.1152/physrev.00023.2009

2. Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF (2010) ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons. EMBO J 29(17):3020–3032. doi: 10.1038/emboj.2010.167

3. De Strooper B, Vassar R, Golde T (2010) The secretases: enzymes with therapeutic potential in Alzheimer disease. Nat Rev Neurol 6(2):99–107. doi: 10.1038/nrneurol.2009.218

4. Vassar R, Kuhn PH, Haass C, Kennedy ME, Rajendran L, Wong PC, Lichtenthaler SF (2014) Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects. J Neurochem 130(1):4–28. doi: 10.1111/jnc.12715

5. Rivera S, Khrestchatisky M, Kaczmarek L, Rosenberg GA, Jaworski DM (2010) Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? J Neurosci 30(46):15337–15357. doi: 10.1523/JNEUROSCI.3467-10.2010

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