Gefitinib induces EGFR and α5β1 integrin co-endocytosis in glioblastoma cells
Author:
Funder
Ligue Contre le Cancer
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00018-020-03686-6.pdf
Reference63 articles.
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2. Brennan CW, Verhaak RGW, McKenna A et al (2013) The somatic genomic landscape of glioblastoma. Cell 155:462–477. https://doi.org/10.1016/j.cell.2013.09.034
3. An Z, Aksoy O, Zheng T et al (2018) Epidermal growth factor receptor (EGFR) and EGFRvIII in glioblastoma (GBM): signaling pathways and targeted therapies. Oncogene 37:1561–1575. https://doi.org/10.1038/s41388-017-0045-7
4. Taylor TE, Furnari FB, Cavenee WK (2012) Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance. Curr Cancer Drug Targets 12:197–209
5. Mellinghoff IK, Cloughesy TF, Mischel PS (2007) PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors. Clin Cancer Res 13:378–381. https://doi.org/10.1158/1078-0432.CCR-06-1992
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