Circ-sh3rf3/GATA-4/miR-29a regulatory axis in fibroblast–myofibroblast differentiation and myocardial fibrosis

Author:

Ma Cai-Xia,Wei Zhi-Ru,Sun Tong,Yang Ming-Hui,Sun Yu-Qie,Kai Kun-Lun,Shi Jia-Chen,Zhou Meng-Jiao,Wang Zi-Wei,Chen Jing,Li Wei,Wang Tian-Qi,Zhang Shan-Feng,Xue Lixiang,Zhang Min,Yin Qianqian,Zang Ming-XiORCID

Funder

National Natural Science Foundation of China

Science and Technology Innovation Talents in Universities of Henan Province

2022 Henan Province Science and Technology R&D Program Joint Fund

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Reference54 articles.

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2. Caja L, Dituri F, Mancarella S, Caballero-Diaz D, Moustakas A, Giannelli G, Fabregat I (2018) TGF-beta and the tissue microenvironment: relevance in fibrosis and cancer. Int J Mol Sci 19:1294. https://doi.org/10.3390/ijms19051294

3. Chothani S, Schafer S, Adami E, Viswanathan S, Widjaja AA, Langley SR, Tan J, Wang M, Quaife NM, Jian Pua C, D’Agostino G, Guna Shekeran S, George BL, Lim S, Yiqun Cao E, van Heesch S, Witte F, Felkin LE, Christodoulou EG, Dong J, Blachut S, Patone G, Barton PJR, Hubner N, Cook SA, Rackham OJL (2019) Widespread translational control of fibrosis in the human heart by RNA-binding proteins. Circulation 140:937–951. https://doi.org/10.1161/CIRCULATIONAHA.119.039596

4. de Salvi GF, de Moraes WM, Bozi LH, Souza PR, Antonio EL, Bocalini DS, Tucci PJ, Ribeiro DA, Brum PC, Medeiros A (2017) Dexamethasone-induced cardiac deterioration is associated with both calcium handling abnormalities and calcineurin signaling pathway activation. Mol Cell Biochem 424:87–98. https://doi.org/10.1007/s11010-016-2846-3

5. Dey S, Kwon JJ, Liu S, Hodge GA, Taleb S, Zimmers TA, Wan J, Kota J (2020) miR-29a is repressed by MYC in pancreatic cancer and its restoration drives tumor-suppressive effects via downregulation of LOXL2. Mol Cancer Res MCR 18:311–323. https://doi.org/10.1158/1541-7786.MCR-19-0594

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