Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome-Reference-Cited by-同舟云学术

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome

Published:2015-09-07 Issue:4 Volume:73 Page:883-900
ISSN:1420-682X
Container-title:Cellular and Molecular Life Sciences
language:en
Short-container-title:Cell. Mol. Life Sci.

Author:

Ashford Anne L.,Dunkley Tom P. J.,Cockerill Mark,Rowlinson Rachel A.,Baak Lisa M.,Gallo Raffaella,Balmanno Kathryn,Goodwin Louise M.,Ward Richard A.,Lochhead Pamela A.,Guichard Sylvie,Hudson Kevin,Cook Simon J.

Funder

Biotechnology and Biological Sciences Research Council (GB)

Association for International Cancer Research (GB)

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00018-015-2032-x.pdf

Reference57 articles.

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2. Becker W, Joost HG (1999) Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity. Prog Nucleic Acid Res Mol Biol 62:1–17 (PubMed 9932450)

3. Aranda S, Laguna A, de la Luna S (2011) DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles. FASEB J 25:449–462. doi: 10.1096/fj.10-165837

4. Han J, Miranda-Saavedra D, Luebbering N, Singh A, Sibbet G, Ferguson MA, Cleghon V (2012) Deep evolutionary conservation of an intramolecular protein kinase activation mechanism. PLoS One 7:e29702. doi: 10.1371/journal.pone.0029702

5. Himpel S, Panzer P, Eirmbter K, Czajkowska H, Sayed M, Packman LC, Blundell T, Kentrup H, Grotzinger J, Joost HG, Becker W (2001) Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A. Biochem J 359:497–505

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