Re-expression of epigenetically silenced PTPRR by histone acetylation sensitizes RAS-mutant lung adenocarcinoma to SHP2 inhibition
Author:
Funder
National Natural Science Foundation of China
CAMS Innovation Fund for Medical Sciences
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00018-023-05034-w.pdf
Reference36 articles.
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3. Simanshu DK, Nissley DV, McCormick F (2017) RAS proteins and their regulators in human disease. Cell 170:17–33
4. Network CGAR (2018) Comprehensive molecular profiling of lung adenocarcinoma. Nature 511:543
5. Huang L, Guo Z, Wang F et al (2021) KRAS mutation: from undruggable to druggable in cancer. Signal Transduct Target Ther 6:386
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