Studies of ApoD−/− and ApoD−/−ApoE−/− mice uncover the APOD significance for retinal metabolism, function, and status of chorioretinal blood vessels

Author:

El-Darzi Nicole,Mast NataliaORCID,Petrov Alexey M.ORCID,Dao Tung,Astafev Artem A.,Saadane Aicha,Prendergast Erin,Schwarz Emmy,Bederman Ilya,Pikuleva Irina A.ORCID

Funder

National Eye Institute

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Reference124 articles.

1. Fliesler SJ, Bretillon L (2010) The ins and outs of cholesterol in the vertebrate retina. J Lipid Res 51:3399–3413. https://doi.org/10.1194/jlr.R010538

2. Pikuleva IA, Curcio CA (2014) Cholesterol in the retina: the best is yet to come. Prog Retin Eye Res 41:64–89. https://doi.org/10.1016/j.preteyeres.2014.03.002

3. Tserentsoodol N, Gordiyenko NV, Pascual I et al (2006) Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class b scavenger receptors. Mol Vis 12:1319–1333

4. Tserentsoodol N, Sztein J, Campos M et al (2006) Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process. Mol Vis 12:1306–1318

5. Mahley RW (2016) Central nervous system lipoproteins: APOE and regulation of cholesterol metabolism. Arterioscler Thromb Vasc Biol 36:1305–1315. https://doi.org/10.1161/ATVBAHA.116.307023

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