Functional Outcomes of Emergency Surgery for Perforated Diverticulitis, Hinchey Grade III

Author:

Samuelsson Andreas12,Bock David13,Prytz Mattias24,Block Mattias15,Ehrencrona Carolina1,Wedin Anette15,Angenete Eva15,Haglind Eva15

Affiliation:

1. Department of Surgery, SSORG – Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden

2. Department of Surgery, Region Västra Götaland NU‐Hospital Group Trollhättan Sweden

3. BioPharma Early Biometrics and Statistical Innovation, Data Science & AI, BioPharmaceuticals R&D AstraZeneca Gothenburg Sweden

4. Department of Research and Development NU‐Hospital Group Trollhättan Sweden

5. Department of Surgery, Region Västra Götaland Sahlgrenska University Hospital Gothenburg Sweden

Abstract

AbstractBackgroundLaparoscopic lavage as a treatment for perforated diverticulitis, Hinchey III, has been found safe and feasible in randomized trials. A few studies have reported functional outcomes and quality of life as secondary outcomes. This study investigated distress associated with dysfunction of the bowel or stoma, functional outcomes, and quality of life 2–3 years after surgery in a national unselected cohort.MethodsAll patients in Sweden who underwent emergency surgery for perforated diverticulitis with purulent peritonitis (2016–2018) were invited to answer a comprehensive, study‐specific questionnaire 2–3 years after the index surgery.ResultsOut of 499 potential patients, 226 returned the questionnaire, and 209 were included in the analysis. There was no statistically significant difference between laparoscopic lavage and resection in distress associated with dysfunction of the bowel or stoma (odds ratio [OR], 1.32 [95% CI, 0.91–1.92]; p = 0.015). Bowel dysfunction measured by the LARS score was significantly higher for the lavage group (OR, 1.65 [95% CI, 1.11–2.45]), while stoma was more frequent after resection surgery (40 vs 6%).ConclusionsPatients experienced long‐term distress from bodily dysfunction after emergency surgery for perforated diverticulitis regardless of the technique used. Regular follow‐up could benefit these patients.Trial RegistrationThe project was registered at ClinicalTrials.gov on 2017–11‐06. Identifier: NCT03332550. Acronym: LapLav.

Funder

Göteborgs Läkaresällskap

Göteborgs Universitet

Eriksson Brothers Foundation

Grants from the Swedish state under the agreement between the Swedish government and the county councils, the ALF-agreement

University of Gothenburg

Publisher

Wiley

Subject

Surgery

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