Affiliation:
1. Department of Neurosurgery Peking University Third Hospital 49 North Garden Road, Haidian District 100191 Beijing China
2. Department of Radiology Peking University Third Hospital Beijing China
Abstract
AbstractObjectiveTo compare the differences in the short‐term recovery from neurological symptoms (SRN) (≤ 6 months) and clinical characteristics of patients with different Shamblin classifications carotid body tumor (CBT) resection and to analyze the risk factors affecting SRN after surgery.MethodsPatients who underwent CBT resection between June 2018 and September 2022 were recruited. Perioperative factors and indicators of the nature of the tumor were recorded. The risk factors affecting SRN after CBT resection were analyzed using logistic regression analysis.ResultsEighty‐five patients (43.86 ± 12.7 years, 46 females) were included, 40 (47.06%) of whom exhibited SRN. Univariate logistic regression showed that preoperative symptoms, surgical side, bilateral posterior communicating artery (PcoA) opening, some indicators of tumor size, operative/anesthesia time, and Shamblin III classification were correlated with postoperative neurological prognosis (all p < 0.05). After adjusting for confounders, preoperative symptoms (OR, 5.072; 95% CI 1.027–25.052; p = 0.046), surgical side (OR, 0.025; 95% CI 0.003–0234; p = 0.001), bilateral PcoA opening (OR, 22.671; 95% CI 2.549–201.666; p = 0.005), distance from the tip of the C2 dens to the superior aspect (dens‐CBT) (OR, 0.918; 95% CI 0.858–0.982; p = 0.013) and Shamblin III classification (OR, 28.488; 95% CI 1.986–408.580; p = 0.014) were correlated with postoperative neurological symptom recovery.ConclusionPreoperative symptoms, surgical side (right), bilateral PcoA opening, a short dens‐CBT and Shamblin III classification are risk factors affecting SRN after CBT resection. Early resection is recommended for small‐volume CBTs without neurovascular compression or invasion to obtain SRN.
Funder
National Natural Science Foundation of China