Reliable diagnosis of IDH-mutant glioblastoma by 2-hydroxyglutarate detection: a study by 3-T magnetic resonance spectroscopy

Author:

Natsumeda ManabuORCID,Motohashi Kunio,Igarashi Hironaka,Nozawa Takanori,Abe Hideaki,Tsukamoto Yoshihiro,Ogura Ryosuke,Okada Masayasu,Kobayashi Tsutomu,Aoki Hiroshi,Takahashi Hitoshi,Kakita Akiyoshi,Okamoto Kouichirou,Nakada Tsutomu,Fujii Yukihiko

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical),General Medicine,Surgery

Reference28 articles.

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2. Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, VE V, Vogelstein B, Bigner DD (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765–773. https://doi.org/10.1056/NEJMoa0808710

3. Polivka J, Polivka J Jr, Rohan V, Pesta M, Repik T, Pitule P, Topolcan O (2014) Isocitrate dehydrogenase-1 mutations as prognostic biomarker in glioblastoma multiforme patients in West Bohemia. Biomed Res Int 2014:735659. https://doi.org/10.1155/2014/735659

4. Ogura R, Tsukamoto Y, Natsumeda M, Isogawa M, Aoki H, Kobayashi T, Yoshida S, Okamoto K, Takahashi H, Fujii Y, Kakita A (2015) Immunohistochemical profiles of IDH1, MGMT and P53: practical significance for prognostication of patients with diffuse gliomas. Neuropathology 35:324–335. https://doi.org/10.1111/neup.12196

5. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Ellison DW, Figarella-Branger D, Perry A, Reifenberger G, von Deimling A (2016) WHO classification of tumours of the central nervous system. IARC, Lyon

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