Evolving Landscape of Clinical Trials in Heart Failure: Patient Populations, Endpoint Selection, and Regions of Enrollment-Reference-Cited by-同舟云学术

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Evolving Landscape of Clinical Trials in Heart Failure: Patient Populations, Endpoint Selection, and Regions of Enrollment

Published:2018-01-19 Issue:1 Volume:15 Page:10-16
ISSN:1546-9530
Container-title:Current Heart Failure Reports
language:en
Short-container-title:Curr Heart Fail Rep

Author:

Samman Tahhan Ayman,Vaduganathan Muthiah,Greene Stephen J.,Okafor Maureen,Kumar Sonali,Butler Javed

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Emergency Medicine

Link

http://link.springer.com/article/10.1007/s11897-018-0374-z/fulltext.html

Reference47 articles.

1. Neuman MD, Goldstein JN, Cirullo MA, Schwartz JS. Durability of class I American College of Cardiology/American Heart Association clinical practice guideline recommendations. JAMA. 2014;311(20):2092–100. https://doi.org/10.1001/jama.2014.4949 .

2. •• Gheorghiade M, Vaduganathan M, Greene SJ, Mentz RJ, Adams KF Jr, Anker SD, et al. Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions. Heart Fail Rev. 2014;19:135–52. This analysis of more than 150 heart failure trials published in major journals between 2001-2012 provides details on enrollment rates and key trial-level characteristics.

3. Greene SJ, Shah AN, Butler J, Ambrosy AP, Anker SD, Chioncel O, et al. Designing effective drug and device development programs for hospitalized heart failure: a proposal for pretrial registries. Am Heart J. 2014;168(2):142–9. https://doi.org/10.1016/j.ahj.2014.05.009 .

4. • Baldi ILC, Berchialla P, Gregori D. Early termination of cardiovascular trials as a consequence of poor accrual: analysis of ClinicalTrials.gov 2006–2015. BMJ Open. 2017;7:e013482. This is a recent analysis of ClinicalTrials.gov database which showed that poor accrual was the most common reason for trials failing to complete.

5. •• Samman Tahhan A, Vaduganathan M, Kelkar A, Georgiopoulou VV, Kalogeropoulos AP, Greene SJ, et al. Trends in heart failure clinical trials from 2001-2012. J Card Fail. 2016;22(3):171–9. https://doi.org/10.1016/j.cardfail.2015.06.014 . This analysis of more than 150 heart failure trials published in major journals between 2001-2012 provides details on enrollment rates and key trial-level characteristics.

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Baroreflex activation therapy with the Barostim ™ device in patients with heart failure with reduced ejection fraction: a patient level meta‐analysis of randomized controlled trials;European Journal of Heart Failure;2022-07-03

2. Pragmatic Design of Randomized Clinical Trials for Heart Failure;JACC: Heart Failure;2021-05

3. Building a Heart Failure Clinic: A Practical Guide from the Heart Failure Society of America;Journal of Cardiac Failure;2021-01

4. Does asymmetry in patient recruitment in large critical care trials follow the Pareto principle?;Trials;2020-05-05

5. First granted example of novel FDA trial design under Expedited Access Pathway for premarket approval: BeAT-HF;American Heart Journal;2018-10

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