Author:
Tran Patrick,Banerjee Prithwish
Abstract
Abstract
Purpose of Review
To provide an overview of the potential iatrogenic causes of acute decompensated heart failure (AHF) and an evidence-based management strategy to address this.
Recent Findings
As the heart failure (HF) population continues to age and become burdened with greater comorbidities and polypharmacy, patients become more susceptible to the iatrogenic precipitants of HF. The following clinical scenarios are familiar to clinicians, but the sequelae to AHF are often unanticipated: HF medications withdrawn during an intercurrent illness and not restarted, cardiotoxic therapy prescribed for cancer without timely and regular monitoring of left ventricular function, excessive intravenous fluids administered for sepsis or postoperatively, a blood transfusion volume not adjusted for body weight, iatrogenic anaemia that goes unnoticed or an inappropriate type of pacemaker implanted in a patient with underlying left ventricular systolic dysfunction.
Summary
Iatrogenic decompensated HF is a phenomenon that is infrequently documented in the literature but increasingly confronted by clinicians of all specialties. It is associated with a high mortality and morbidity rate. By having greater awareness of these triggers, iatrogenic AHF should be one that is prevented rather than managed when it occurs.
Publisher
Springer Science and Business Media LLC
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,Emergency Medicine
Reference63 articles.
1. Ponikowski P, Voors AA. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Eur Heart J. 2016;37:2129–200.
2. National Heart Failure Audit (NHFA) April 2015 – March 2016. National Institute for Cardiovascular Outcomes Research (NICOR), Institute of Cardiovascular Science, University College London. 2016. http://www.ucl.ac.uk/nicor/audits/heartfailure/documents/annualreports/annual-report2015–6-v8.pdf. Accessed at 21 Sept 2019.
3. Rich M, Shah A, Vinson J, et al. Iatrogenic congestive heart failure in older adults: clinical course and prognosis. J Am Geriatr Soc. 1996;44:638–43.
4. Burnett H, Earley A, Voors AA, et al. Thirty years of evidence on the efficacy of drug treatments for chronic heart failure with reduced ejection fraction: a network meta-analysis. Circ Heart Fail. 2017;10:e003529.
5. McMurray JJV, Solomon SD, Inzucchi SE, et al. Dapagliflozin in patients with heart failure and reduced ejection fraction. Engl J Med. 2019;381(21):1995–2008. https://doi.org/10.1056/NEJMoa1911303.
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