Direct comparison of aspirin plus hirudin aspirin plus heparin, and aspirin alone among 12,000 patients with acute myocardial infarction not receiving thrombolysis: Rationale and design of the First American Study of Infarct Survival (ASIS-1)

Author:

Ridker Paul M.,O'Donnell Christopher J.,Hennekens Charles H.

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Hematology

Reference35 articles.

1. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. ISIS-2: Randomized trial of intravenous streptokinase, oral aspirin, both or neither among 17,187 cases of suspected acute myocardial infarction.Lancet 1988;2:349?360.

2. Ridker PM, Hebert PR, Fuster V, Hennekens CH. Are both aspirin and heparin justified as adjuncts to thrombolytic therapy for acute myocardial infarction?Lancet 1993;341:1574?1577.

3. MacMahon S, Collins R, Knight C, Yusuf S, Peto R. Reduction in major morbidity and mortality by heparin in acute myocardial infarction (abstr).Circulation 1988;78(Suppl II):98.

4. Chalmers TC, Matta RJ, Smith H, Kunzler AM. Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction.N Engl J Med 1977;297:1091?1096.

5. LATE Study Group. Late assessment of thrombolytic efficacy (LATE) study with alteplase 6?24 hours after onset of acute myocardial infarction.Lancet 1993;342:759?765.

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