Ex-Vivo TCR αβ and CD19 Depleted Haploidentical Stem Cell Transplantation with CD45RO Memory T Cell Addback for CARD11 Deficiency

Author:

Bartakke SandipORCID,Iyer PrasadORCID

Publisher

Springer Science and Business Media LLC

Reference5 articles.

1. Stepensky P, Keller B, Buchta M, Kienzler AK, Elpeleg O, Somech R, Cohen S, Shachar I, Miosge LA, Schlesier M, Fuchs I (2013) Deficiency of caspase recruitment domain family member 11 (CARD11), causes profound combined immunodeficiency in human subjects. J Allergy Clin Immunol 131(2):477–485

2. Greil J, Rausch T, Giese T, Bandapalli OR, Daniel V, Bekeredjian-Ding I, Stütz AM, Drees C, Roth S, Ruland J, Korbel JO (2013) Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency. J Allergy Clin Immunol 131(5):1376–1383

3. Fuchs S, Rensing-Ehl A, Pannicke U, Lorenz MR, Fisch P, Jeelall Y, Rohr J, Speckmann C, Vraetz T, Farmand S, Schmitt-Graeff A, Krüger M, Strahm B, Henneke P, Enders A, Horikawa K, Goodnow C, Schwarz K, Ehl S (2015) Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency. Blood 126(14):1658–1669. https://doi.org/10.1182/blood-2015-03-631374

4. Dunaikina M, Zhekhovtsova Z, Shelikhova L, Glushkova S, Nikolaev R, Blagov S, Khismatullina R, Balashov D, Kurnikova E, Pershin D, Muzalevskii Y (2021) Safety and efficacy of the low-dose memory (CD45RA-depleted) donor lymphocyte infusion in recipients of αβ T cell-depleted haploidentical grafts: results of a prospective randomized trial in high-risk childhood leukemia. Bone Marrow Transpl 56(7):1614–1624

5. Touzot F, Neven B, Dal-Cortivo L, Gabrion A, Moshous D, Cros G, Chomton M, Luby JM, Terniaux B, Magalon J, Picard C (2015) CD45RA depletion in HLA-mismatched allogeneic hematopoietic stem cell transplantation for primary combined immunodeficiency: a preliminary study. J Allergy Clin Immunol 135(5):1303–1309

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