A Prospective Study to Evaluate the Effect of Therapeutic Drug Monitoring-Based Posaconazole Prophylaxis on Invasive Fungal Infection Rate During Acute Myeloid Leukemia Induction Therapy

Author:

Boppana Mounika,Sengar ManjuORCID,Jain HasmukhORCID,Gurjar Murari,Ambotkar Madhavi,Gota VikramORCID,Bonda Avinash,Bagal BhausahebORCID,Thorat Jayashree,Gokarn Anant,Nayak LingarajORCID,Shetty Nitin,Baheti Akshay,Mokal Smruti,Kannan Sadhana,Shetty Alok,Eipe ThomasORCID

Funder

Tata Memorial Centre Research Administrative Council

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference50 articles.

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2. Cacciapuoti A, Loebenberg D, Corcoran E et al (2000) In vitro and in vivo activities of SCH 56592 (posaconazole), a new triazole antifungal agent, against Aspergillus and Candida. Antimicrob Agents Chemother 44(8):2017–2022. https://doi.org/10.1128/AAC.44.8.2017-2022.2000

3. Manavathu EK, Cutright JL, Loebenberg D, Chandrasekar PH (2000) A comparative study of the in vitro susceptibilities of clinical and laboratory-selected resistant isolates of Aspergillus spp. to amphotericin B, itraconazole, voriconazole and posaconazole (SCH 56592). J Antimicrob Chemother 46(2):229–234. https://doi.org/10.1093/jac/46.2.229

4. Pfaller MA, Messer SA, Hollis RJ, Jones RN (2001) In vitro activities of posaconazole (Sch 56592) compared with those of itraconazole and fluconazole against 3,685 clinical isolates of Candida spp. and Cryptococcus neoformans. Antimicrob Agents Chemother 45(10):2862–2864. https://doi.org/10.1128/AAC.45.10.2862-2864.2001

5. Pfaller MA, Messer SA, Hollis RJ, Jones RN (2002) Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance Program, 2000. Antimicrob Agents Chemother 46(4):1032–1037. https://doi.org/10.1128/AAC.46.4.1032-1037.2002

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1. Approaches for posaconazole therapeutic drug monitoring and their clinical benefits;European Journal of Clinical Pharmacology;2024-09-09

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