Antigen recognition and targeted delivery by the single-chain Fv
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Biophysics
Link
http://link.springer.com/content/pdf/10.1007/BF03033874.pdf
Reference108 articles.
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3. Fleischman J. B., Porter, R. R., and Press, E. M. (1963) The arrangement of the peptide chains in γ-globulin.Biochem. J. 88, 220–228.
4. Köhler, G. and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity.Nature 245, 495–497.
5. Huston, J. S., Levinson, D., Mudgett-Hunter, M., Tai., M.-S., Novotny, J., Margolies, M. N., Ridge, R. J., Bruccoleri, R., Haber E., Crea, R., and Opperman, H. (1988) Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced inEscherichia coli.Proc. Natl. Acad. Sci. USA 85, 5879–5883.
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