Abstract
AbstractGalactoceles are benign lesions formed at the expense of breast glandular tissue. Its occurrence in boys is exceptional, with isolated reports in the scientific literature. We present the case of a 2-year-old boy who debuted with a unilateral breast enlargement of 18 months of evolution, with no other associated symptoms. Initial hormonal study showed no alterations. Ultrasonography showed the presence of a homogeneous 5-cm retroareolar cyst. Surgical excision was indicated. During the procedure, abundant milk drained from the lesion. The histopathological study, supported by GATA-3 immunohistochemical staining, confirmed the diagnosis of galactocele. The range of possible differential diagnoses for unilateral or bilateral breast enlargement in boys is wide and includes neoplastic, vascular, and hormonal etiologies. Galactocele, which is an exceptional entity in this group, should be considered. Immunohistochemical techniques such as GATA-3, characteristic of the breast epithelium, can contribute to the diagnosis.
Publisher
Springer Science and Business Media LLC
Reference7 articles.
1. Perez-Bóscollo AC, Dutra RA, Borges LG, Stafuzza Gonçalves EM, Etchebehere RM, Rocha RL et al (2009) Galactocele: an unusual cause of breast enlargement in children. J Pediatr Surg 44(7):e1-3
2. Javed A, Lteif A (2013) Development of the human breast. Semin Plast Surg 27(1):5–12
3. Güven A, Hancili S (2013) Bilateral galactocele in a male infant with Down syndrome and congenital hypothyroidism. Pediatr Int 55(5):e116–e118
4. Rahman N, Davenport M, Buchanan C (2004) Galactocele in a male infant with congenital hypopituitarism. J Pediatr Endocrinol Metab 17(10):1451–1453
5. Lau CT, Wong KK, Tam P (2016) Galactocele in a male infant with transient hyperprolactinaemia: an extremely rare cause of breast enlargement in children. Case Rep Pediatr 2016:9487616