The importance of endpoint selection: How effective does a drug need to be for success in a clinical trial of a possible Alzheimer’s disease treatment?-Reference-Cited by-同舟云学术

The importance of endpoint selection: How effective does a drug need to be for success in a clinical trial of a possible Alzheimer’s disease treatment?

Published:2018-03-23 Issue:7 Volume:33 Page:635-644
ISSN:0393-2990
Container-title:European Journal of Epidemiology
language:en
Short-container-title:Eur J Epidemiol

Author:

Evans Stephanie^ORCID,McRae-McKee Kevin,Wong Mei Mei,Hadjichrysanthou Christoforos,De Wolf Frank,Anderson Roy

Funder

This study was funded by the Janssen Prevention Center

Publisher

Springer Science and Business Media LLC

Subject

Epidemiology

Link

http://link.springer.com/article/10.1007/s10654-018-0381-0/fulltext.html

Reference39 articles.

1. Alzheimer’s Disease International. World Alzheimer’s Report. Alzheimer’s Disease International. 2016. https://www.alz.co.uk/research/world-report-2016 . Accessed 30 Mar 2017.

2. Biagioni MC, Galvin JE. Using biomarkers to improve detection of Alzheimer’s disease. Neurodegener Dis Manag. 2011;1:127–39.

3. Patel V. Deaths registered in England and Wales (series DR): 2015—Office for National Statistics. Office for National Statistics. 2016. https://www.ons.gov.uk/releases/deathsregisteredinenglandandwalesseriesdr2013 . Accessed 28 Apr 2017.

4. Schneider LS, Mangialasche F, Andreasen N, Feldman H, Giacobini E, Jones R, et al. Clinical trials and late-stage drug development for Alzheimer’s disease: an appraisal from 1984 to 2014. J Intern Med. 2014;275:251–83.

5. EMA. European Medicines Agency Committee for Medicinal Products for Human Use. Draft guideline on the clinical investigation of medicines for the treatment of Alzheimer’s disease and other dementias. 2016. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2016/02/WC500200830.pdf .

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A large-scale multi-centre study characterising atrophy heterogeneity in Alzheimer’s disease;2024-08-28

2. Mobility-Based Smartphone Digital Phenotypes Unobtrusively Capture Everyday Cognition, Mood, and Community Life-Space in Older Adults: A Pilot Study (Preprint);2024-04-29

3. Toward the right treatment at the right time: Modeling the trajectory of cognitive decline to identify the earliest age of change in people with Alzheimer's disease;Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring;2024-01

4. Effect of hearing aids on cognitive functions in middle-aged and older adults with hearing loss: A systematic review and meta-analysis;Frontiers in Aging Neuroscience;2022-11-14

5. Assessing the Clinical Meaningfulness of the Alzheimer’s Disease Composite Score (ADCOMS) Tool;Neurology and Therapy;2022-05-05