Transcription of chemically acetylated chromatin with homologous RNA polymerase B-Reference-Cited by-同舟云学术

Transcription of chemically acetylated chromatin with homologous RNA polymerase B

Published:1984-02-01 Issue:2 Volume:4 Page:155-163
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Csordas A.¹²,Multhaup I.¹,Grunicke H.¹

Affiliation:

1. Institute for Medical Chemistry and Biochemistry, University of Innsbruck, Innsbruck, Austria

2. Universität Innsbruck, Institut fü Medizinische Chemie und Biochemie, A-6020 Innsbruck, Fritz-Pregl-Str. 3, Austria

Abstract

Homologous RNA polymerase B was used to examine the template properties of rat liver chromatin modified by acetic anhydride. Transcription of chromatin was strongly stimulated on the chemically acetyiated template. Under conditions of reinitiation inhibition there was an approximately two-fold increase in the number of initiation sites on the acetylated chromatin. A new method of chemical acetylation of histones, with a high degree of specificity, is presented.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/4/2/155/519151/bsr0040155.pdf

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