Abstract
AbstractThe use of bio-based raw materials in the manufacture of customized aerogels has increased significantly over the last decade. Combining the advantages of biopolymer sustainability and lower costs when producing aerogels in particulate form, agar aerogel particles were fabricated in this study. They were prepared by successive thermal gelation, ethanol solvent exchange, wet milling and supercritical CO2 assisted drying. The particles still maintain high porosity (~ 1.0 cm3 g−1) and high specific surface areas (210–270 m2 g−1). The stability in wound fluid substitutes, liquid holding capacity, and cytocompatibility of these agar-based aerogel particles may make them an advantageous wound-dressing matrix that can be further customized for particular applications by adding wound-active/reactive substances, such as antibiotics, antioxidants, immunoreactive drugs or growth factors.
Graphical abstract
Funder
Deutsche Forschungsgemeinschaft
Technische Universität Hamburg
Publisher
Springer Science and Business Media LLC
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