Safety, Pharmacokinetics and Pharmacodynamics of TNHH, a Novel Targeted Neutrophil-Inhibitory Hirulog Hybrid Glycoprotein, in Healthy Volunteers-Reference-Cited by-同舟云学术

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Safety, Pharmacokinetics and Pharmacodynamics of TNHH, a Novel Targeted Neutrophil-Inhibitory Hirulog Hybrid Glycoprotein, in Healthy Volunteers

Published:2019-05-15 Issue:6 Volume:33 Page:605-614
ISSN:1172-7047
Container-title:CNS Drugs
language:en
Short-container-title:CNS Drugs

Author:

Gou Zhong Ping,Song Zi Hui,Chen Xiao Gang,Hu Xiao Cheng,Wang Ying,Fan Kai,Cai Yong Ming,Zheng Li

Funder

Ministry of Science and Technology of China

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Psychiatry and Mental health,Clinical Neurology

Link

http://link.springer.com/content/pdf/10.1007/s40263-019-00628-0.pdf

Reference22 articles.

1. Wardlaw JM, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley RL, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet. 2012;379(9834):2364–72.

2. Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. 2018 Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46–110.

3. Tsivgoulis G, Geisler F, Katsanos AH, Korv J, Kunz A, Mikulik R, et al. Ultraearly intravenous thrombolysis for acute ischemic stroke in mobile stroke unit and hospital settings. Stroke. 2018;49(8):1996–9.

4. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, et al. Thrombolysis with alteplase 3–4.5 h after acute ischemic stroke. N Engl J Med. 2008;359(13):1317–29.

5. Gurman P, Miranda OR, Nathan A, Washington C, Rosen Y, Elman NM. Recombinant tissue plasminogen activators (rtPA): a review. Clin Pharmacol Ther. 2015;97(3):274–85.

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