Pregnancy and Lung Transplantation
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Earth and Planetary Sciences,General Environmental Science
Link
https://link.springer.com/content/pdf/10.1007/s13665-021-00274-2.pdf
Reference41 articles.
1. Chambers DC, Cherikh WS, Harhay MO, Hayes D Jr, Hsich E, Khush KK, et al. International Society for Heart and Lung Transplantation. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult lung and heart-lung transplantation Report-2019; Focus theme: Donor and recipient size match. J Heart Lung Transplant. 2019;38(10):1042–55. https://doi.org/10.1016/j.healun.2019.08.001.
2. Donaldson S, Novotny D, Paradowski L, Aris R. Acute and chronic lung allograft rejection during pregnancy. Chest. 1996;110(1):293–6. https://doi.org/10.1378/chest.110.1.293.
3. Gyi KM, Hodson ME, Yacoub MY. Pregnancy in cystic fibrosis lung transplant recipients: case series and review. J Cyst Fibros. 2006;5(3):171–5. https://doi.org/10.1016/j.jcf.2006.03.001.
4. Thakrar MV, Morley K, Lordan JL, Meachery G, Fisher AJ, Parry G, et al. Pregnancy after lung and heart-lung transplantation. J Heart Lung Transplant. 2014;33(6):593–8. https://doi.org/10.1016/j.healun.2014.02.008In a recent retrospective review of 19 lung transplant recipients, Thakrar and colleagues describe the impact of pregnancy on lung function and calcineurin inhibitor levels which may have a bearing on future graft function. In the absence of rejection, lung function remained relatively stable through pregnancy. Fall in the trough calcineurin levels occurred in the first trimester and dose escalation was needed.
5. Bry C, Hubert D, Reynaud-Gaubert M, Dromer C, Mal H, Roux A, et al. Pregnancy after lung and heart-lung transplantation: a French multicentre retrospective study of 39 pregnancies. ERJ Open Res. 2019;5(4):00254–2018. https://doi.org/10.1183/23120541.00254-2018In a recent retrospective review, Bry and colleagues reported on 39 pregnancies from 11 French centers. This is one of the largest cohorts of pregnancies in women with lung and heart-lung transplantation. They showed that low birth weight (48%) and preterm birth (43%) were common in infants born to lung transplant recipients. Moreover, one in three recipients developed chronic lung allograft dysfunction after pregnancy.
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