Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae
Author:
Publisher
Wiley
Subject
Cell Biology,Organic Chemistry,Biochemistry
Reference37 articles.
1. Mercer, E.I. (1991) Sterol Synthesis Inhibitors: Their Current Status and Modes of Action, Lipids 26, 584–597.
2. Abe, I., and Prestwich, G.D. (1999) Squalene Epoxidase and Oxidosqualene Lanosterol Cyclase—Key Enzymes in Cholesterol Biosynthesis, in Comprehensive Natural Products Chemistry. Isoprenoid Including Carotenoids and Steroids (Cane, D., ed.), Vol. 2, pp. 267–298, Elsevier, Oxford, United Kingdom.
3. Urbina, J.A. (1997) Lipid Biosynthesis Pathways as Chemotherapeutic Targets in Kinetoplastid Parasites, Parasitology 114, S91-S99.
4. Coppens, I., and Courtoy, P.J. (1995) Exogenous and Endogenous Sources of Sterols in the Culture-Adapted Procyclic Trypomastigotes of Trypanosoma brucei, Mol. Biochem. Parasitol. 73, 179–188.
5. Contreras, L.M., Vivas, J., and Urbina, J.A. (1997) Altered Lipid Composition and Enzyme Activities of Plasma Membranes from Trypanosoma (Schizotrypanum) cruzi Epimastigotes Grown in the Presence of Sterol Biosynthesis Inhibitors, Biochem. Pharmacol. 53, 697–704.
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