4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase
Author:
Affiliation:
1. ; Department of Science and Drug Technology; University of Torino; Via P. Giuria 9 Turin 10125 Italy
Publisher
Wiley
Subject
Cell Biology,Organic Chemistry,Biochemistry
Link
http://link.springer.com/article/10.1007/s11745-016-4173-6/fulltext.html
Reference20 articles.
1. Meiosis-activating sterols: background, discovery, and possible use;Byskov;J Mol Med,1998
2. Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis;Marijanovic;Mol Endocrinol,2003
3. In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity;Mo;Biochim Biophys Acta,2003
4. Malformation syndromes caused by disorders of cholesterol synthesis;Porter;J Lipid Res,2011
5. RNA interference characterization of proteins discovered by proteomic analysis of pancreatic cancer reveals function in cell growth and survival;Lee;Pancreas,2012
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