Lipoxygenase-inhibitory azomethines and benzoylhydrazones. II. Effects of phenylsubstituted azomethines on the antigen-induced contractions of guinea pig lung parenchymal strips and jejunum segments

Author:

Pietzsch W.,Schwabe K. H.,Melchior K.,Grupe R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Toxicology,Pharmacology,Immunology

Reference5 articles.

1. H. Ulbricht, H. Bekemeier, R. Hirschelmann, R. Grupe, B. Böhme and W. Pietzsch,Structure and action of some new phenolic lipoxygenase inhibitors against different lipoxygenases, in models of inflammation, allergy and circulation. 6. Symposium “Potentielle Arzneistoffe”, 24.–26. 3. 1987, Neubrandenburg.

2. H. Bekemeier, R. Hirschelmann, A. Langner, A. J. Giessler, E. Krause, T. Funke, F. Hänsel, H. Schmidt, S. Zarnack, H. H. Schumann and H. Ulbrich,Pharmacology of the lipoxygenase inhibitors oxphaman, 1-(2,5-dihydroxybenzylidene) amino-adamantan, and oxphalin, 1-(3,4-dihydroxybenzylidene)-2,4,6-trimethylalanin. Die Pharmazie44, 550–554 (1989).

3. T. Bahr, B. Böhme, T. Ziska and R. Grupe,Inhibition of the lipoxygenase activity and of the degranulation of mast cells in vitro by phenolic azomethines. 12th European Workshop on Inflammation 1990, Agents and Actions32, 137–139 (1991).

4. R. Grupe and W. Pietzsch,Inhibition of antigen-induced contractions of ileum segments and lung parenchymal strips of actively sensitized guinea pigs by different anti-allergic agents in vitro. Agents and Actions23, 324–327 (1988).

5. F. M. Lehmann, N. Bretz, F. v. Bruchhausen and G. Wurm,Substrates for arachidonic acid co-oxidation with peroxidase/hydrogen peroxide. Biochemical Pharmacology38, 1209–1216 (1989).

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