Etiology and management of acute and recurrent group a Streptococcal tonsillitis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Link
http://link.springer.com/content/pdf/10.1007/s11908-001-0023-6.pdf
Reference70 articles.
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2. Pichichero ME: Group A b-hemolytic streptococcal infections. Pediatr Rev 1998, 19:291–302.A comprehensive review summarizing the causes and management of GAS infections, as well as various theories for failure of penicillin treatment.
3. Scaglione F, Demartini G, Arcidiacono MM, et al.: Optimum treatment of streptococcal pharyngitis. Drugs 1997, 53:86–97.
4. Gillespie SH: Failure of penicillin in Streptococcus pyogenes Infection. Lancet 1998, 352:1954–1955.
5. Neeman R, Keller N, Barzilai A, et al.: Prevalence of internalisation-associated gene, prtF1, among persisting group-a streptococcus strains isolated from asymptomatic carriers. Lancet 1998, 352:1974–1977.An important report showing a significant correlation between continued carriage of GAS despite therapy, and the presence of the prtF1 gene, encoding fibronectin-binding protein, which mediates GAS internalization. The results support the theory that GAS internalization might be associated with intracellular bacterial persistence after antibiotic treatment.
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