Relevant Cytokines in the Management of Community-Acquired Pneumonia
Author:
Funder
CONACYT
CONACTY
PIACYT-UANL
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases
Link
http://link.springer.com/content/pdf/10.1007/s11908-016-0516-y.pdf
Reference58 articles.
1. Johnstone J, Mandell L. Guidelines and quality measures: do they improve outcomes of patients with community-acquired pneumonia? Infect Dis Clin North Am. 2013;27(1):71–86.
2. Wunderink RG, Waterer GW. Clinical practice. Community-acquired pneumonia. N Engl J Med. 2014;370(6):543–51. Major importance: It is an overview of CAP that help us to decide the antibiotic therapy, the extent of testing to determine the cause of pneumonia, and the appropriate location of treatment (home, inpatient floor, or ICU).
3. Sligl WI, Marrie TJ. Severe community-acquired pneumonia. Crit Care Clin. 2013;29(3):563–601. This article show us the epidemiology of severe CAP. Up to 22 % of patients with CAP require ICU admission, with 44 to 83 % requiring mechanical ventilation and up to 50 % presenting with concomitant septic shock.
4. Fernandez-Botran R, Uriarte SM, Arnold FW, et al. Contrasting inflammatory responses in severe and non-severe community-acquired pneumonia. Inflammation. 2014;37(4):1158–66. Major importance: this study compared systemic and local cytokine profiles in patients with severe versus non-severe CAP. Results indicate that patients with severe CAP fail to mount a local pro-inflammatory response but exhibit instead a more substantial systemic inflammatory response.
5. Menendez R, Sahuquillo-Arce JM, Reyes S, et al. Cytokine activation patterns and biomarkers are influenced by microorganisms in community-acquired pneumonia. Chest. 2012;141(6):1537–45. Major importance: There is a different inflammatory patterns elicited by different microorganisms. Recognizing these patterns may facilitate a broader understanding of host inflammatory response to microorganisms.
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