One-Electron Reduction of 6-Hydroxydopamine Quinone is Essential in 6-Hydroxydopamine Neurotoxicity-Reference-Cited by-同舟云学术

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One-Electron Reduction of 6-Hydroxydopamine Quinone is Essential in 6-Hydroxydopamine Neurotoxicity

Published:2013-02-06 Issue:1 Volume:24 Page:94-101
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Villa Monica,Muñoz Patricia,Ahumada-Castro Ulises,Paris Irmgard,Jiménez Ana,Martínez Isabel,Sevilla Francisca,Segura-Aguilar Juan

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1007/s12640-013-9382-7.pdf

Reference35 articles.

1. Arriagada A, Paris I, Sanchez de las Matas MJ, Cardenas S, Castañeda P, Graumann R, Perez-Pastene C, Olea-Azar C, Couve E, Herrero MT, Caviedes P, Segura-Aguilar J (2004) On the neurotoxicity of leukoaminochrome o-semiquinone radical derived of dopamine oxidation: mitochondria damage, necrosis and hydroxyl radical formation. Neurobiol Dis 16:468–477

2. Fernandez-Gomez FJ, Pastor MD, Garcia-Martinez EM, Melero-Fernandez de Mera R, Gou-Fabregas M, Gomez-Lazaro M, Calvo S, Soler RM, Galindo MF, Jordán J (2006) Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression. Neurobiol Dis 24(2):296–307

3. Fuentes P, Paris I, Nassif M, Caviedes P, Segura-Aguilar J (2007) Inhibition of VMAT-2 and DT-Diaphorase induce cell death in a substantia nigra-derived cell line-an experimental cell model for dopamine toxicity studies. Chem Res Toxicol 20:776–783

4. Gee P, Davison AJ (1984) 6-hydroxydopamine does not reduce molecular oxygen directly, but requires a coreductant. Arch Biochem Biophys 231:164–168

5. Glinka Y, Gassen M, Youdim MB (1997) Mechanism of 6-hydroxydopamine neurotoxicity. J Neural Transm Suppl 50:55–66

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