Hinokitiol Offers Neuroprotection Against 6-OHDA-Induced Toxicity in SH-SY5Y Neuroblastoma Cells by Downregulating mRNA Expression of MAO/α-Synuclein/LRRK2/PARK7/PINK1/PTEN Genes-Reference-Cited by-同舟云学术

Hinokitiol Offers Neuroprotection Against 6-OHDA-Induced Toxicity in SH-SY5Y Neuroblastoma Cells by Downregulating mRNA Expression of MAO/α-Synuclein/LRRK2/PARK7/PINK1/PTEN Genes

Published:2018-12-19 Issue:4 Volume:35 Page:945-954
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Varier Krishnapriya Madhu,Sumathi Thangarajan

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1007/s12640-018-9988-x.pdf

Reference37 articles.

1. Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Sci 299(5604):256–259. https://doi.org/10.1126/science.1077209

2. Cheng F, Li X, Li Y, Wang C, Wang T, Liu G, Baskys A, Uéda K, Chan P, Yu S (2011) α-Synuclein promotes clathrin-mediated NMDA receptor endocytosis and attenuates NMDA-induced dopaminergic cell death. J Neurochem 119:815–825. https://doi.org/10.1111/j.1471-4159.2011.07460.x

3. Deng H, Le W, Guo Y, Hunter CB, Xie W, Huang M, Jankovic J (2006) Heterogeneous phenotype in a family with compound heterozygous parkin gene mutations. Arch Neurol 63:273–277. https://doi.org/10.1001/archneur.63.2.273

4. Dias V, Junn E, Mouradian MM (2013) The role of oxidative stress in Parkinson’s disease. J Parkinsons Dis 3:461–491. https://doi.org/10.3233/JPD-130230

5. Drechsel DA, Patel M (2008) Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson’s disease. Free Radic Biol Med 44:1873–1886. https://doi.org/10.1016/j.freeradbiomed.2008.02.008

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Amantadine mitigates the cytotoxic and genotoxic effects of doxorubicin in SH-SY5Y cells and reduces its mutagenicity;Toxicology in Vitro;2024-08

2. Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity;European Journal of Pharmacology;2024-03

3. Protective Effects of Hinokitiol on Neuronal Ferroptosis by Activating the Keap1/Nrf2/HO-1 Pathway in Traumatic Brain Injury;Journal of Neurotrauma;2023-12-28

4. The SH-SY5Y cell line: a valuable tool for Parkinson’s disease drug discovery;Expert Opinion on Drug Discovery;2023-12-19

5. Recent advances in natural products targeting α-synuclein aggregation or clearance in Parkinson's disease;European Journal of Medicinal Chemistry Reports;2023-12